We describe a new species of Cochranella from the Serranía de Huanchaca, Bolivia. The new species possesses a suite of unusual characteristics, most notably dermal glands along its fingers and toes. Cochranella spiculata is reported from Bolivia and we describe the females of that species. New material of C. bejaranoi from Chuquisaca collected during the dry season confirms that spicules develop only during the breeding season in this species. Small round clusters of melanophores appear to be germinal in nature and associated developmentally with spicules in C. bejaranoi.